Results: Seven patients were referred for HBO2within 24 hours of mastectomy. One patient failed to improve despite starting hyperbaric treatment within 24 hours. All other patients manifested successful healing of their mastecto-my skin flaps with acceptable cosmesis after 10HBO2 treatments. The mean relative perfusion of the at-risk area was 13.8% (±3.7%) pre-HBO2 and 101.6%(±37.3%) post-HBO2.The average area at-risk pre-HBO2 was 17.1 cm2and reduced to zero post-HBO2. Relative perfu-sion values after HBO2 were found to be 6.8(±3.4)times greater than those measured prior to HBO2.
Conclusions: A short course of HBO2 may be sufficient to successfully rescue at risk post-mastectomy breast flaps. ICGA is a useful ad-junct for evaluating post-mastectomy breast flap perfusion before and after HBO2 therapy.